What is Propranolol and how does it work?
Propranolol is a non-selective beta-adrenergic receptor antagonist, known more commonly as a beta-blocker.
Propranolol is a first-line treatment option for Essential Tremor (ET) and is successful in reducing tremor intensity and amplitude in up to 70% of patients. It should, however, be noted that complete suppression of ET is very rare.
Propranolol works best for alleviating tremors in the hands and arms, it is less effective for head and voice tremors. Patients with ET that take Propranolol may see marked improvement in their ability to control their tremor and carry out basic tasks such as drinking from a cup or using food utensils. More specialised motor functions, such as threading a needle, may still be too difficult.
The exact mechanism of action of Propranolol for treating tremors is not fully understood, although it is thought that it may work by blocking nerve impulses to the affected muscles.
Treatment is usually started at a low dose and gradually increased until the tremor improves. The risk of side effects grows with increased dosage.









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